This paper analyses women’s economic participation (WEP) in Mexico. The paper tests an econometric model about the influence of various socio-economic factors on WEP. The results show that the main barriers to female participation are the lack of education and the absence of diverse work possibilities in industries such as manufacturing and hoteling. Other factors mentioned in the literature that also affect the WEP were the number of children per household, population density, the Gini coefficient and poverty on each municipality. Therefore, these variables contribute to increasing WEP and should be the focus of any attempt to increase their labor force participation in the formal sector.